BDBM50347632 CHEMBL1803026

SMILES: COc1ccccc1N1CCN(Cc2ccc(OCCCCc3cn(CCCCCCCCCCn4cc(CCCCOc5ccc(CN6CCN(CC6)c6ccccc6OC)cc5OC)nn4)nn3)c(OC)c2)CC1

InChI Key: InChIKey=KGEGCSUUIDNIBO-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50347632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50347632 (CHEMBL1803026) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCCCc3cn(CCCCCCCCCCn4cc(CCCCOc5ccc(CN6CCN(CC6)c6ccccc6OC)cc5OC)nn4)nn3)c(OC)c2)CC1 Show InChI InChI=1S/C60H84N10O6/c1-71-55-25-13-11-23-53(55)67-37-33-65(34-38-67)45-49-27-29-57(59(43-49)73-3)75-41-19-15-21-51-47-69(63-61-51)31-17-9-7-5-6-8-10-18-32-70-48-52(62-64-70)22-16-20-42-76-58-30-28-50(44-60(58)74-4)46-66-35-39-68(40-36-66)54-24-12-14-26-56(54)72-2/h11-14,23-30,43-44,47-48H,5-10,15-22,31-42,45-46H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2short receptor expressed in CHO cells				J Med Chem 54: 4896-903 (2011) Article DOI: 10.1021/jm2004859 BindingDB Entry DOI: 10.7270/Q2RB74ZR
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50347632 (CHEMBL1803026) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCCCc3cn(CCCCCCCCCCn4cc(CCCCOc5ccc(CN6CCN(CC6)c6ccccc6OC)cc5OC)nn4)nn3)c(OC)c2)CC1 Show InChI InChI=1S/C60H84N10O6/c1-71-55-25-13-11-23-53(55)67-37-33-65(34-38-67)45-49-27-29-57(59(43-49)73-3)75-41-19-15-21-51-47-69(63-61-51)31-17-9-7-5-6-8-10-18-32-70-48-52(62-64-70)22-16-20-42-76-58-30-28-50(44-60(58)74-4)46-66-35-39-68(40-36-66)54-24-12-14-26-56(54)72-2/h11-14,23-30,43-44,47-48H,5-10,15-22,31-42,45-46H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human D2long receptor expressed in CHO cells				J Med Chem 54: 4896-903 (2011) Article DOI: 10.1021/jm2004859 BindingDB Entry DOI: 10.7270/Q2RB74ZR
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50347632 (CHEMBL1803026) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCCCc3cn(CCCCCCCCCCn4cc(CCCCOc5ccc(CN6CCN(CC6)c6ccccc6OC)cc5OC)nn4)nn3)c(OC)c2)CC1 Show InChI InChI=1S/C60H84N10O6/c1-71-55-25-13-11-23-53(55)67-37-33-65(34-38-67)45-49-27-29-57(59(43-49)73-3)75-41-19-15-21-51-47-69(63-61-51)31-17-9-7-5-6-8-10-18-32-70-48-52(62-64-70)22-16-20-42-76-58-30-28-50(44-60(58)74-4)46-66-35-39-68(40-36-66)54-24-12-14-26-56(54)72-2/h11-14,23-30,43-44,47-48H,5-10,15-22,31-42,45-46H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3 receptor expressed in CHO cells				J Med Chem 54: 4896-903 (2011) Article DOI: 10.1021/jm2004859 BindingDB Entry DOI: 10.7270/Q2RB74ZR
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Sus scrofa)	BDBM50347632 (CHEMBL1803026) Show SMILES COc1ccccc1N1CCN(Cc2ccc(OCCCCc3cn(CCCCCCCCCCn4cc(CCCCOc5ccc(CN6CCN(CC6)c6ccccc6OC)cc5OC)nn4)nn3)c(OC)c2)CC1 Show InChI InChI=1S/C60H84N10O6/c1-71-55-25-13-11-23-53(55)67-37-33-65(34-38-67)45-49-27-29-57(59(43-49)73-3)75-41-19-15-21-51-47-69(63-61-51)31-17-9-7-5-6-8-10-18-32-70-48-52(62-64-70)22-16-20-42-76-58-30-28-50(44-60(58)74-4)46-66-35-39-68(40-36-66)54-24-12-14-26-56(54)72-2/h11-14,23-30,43-44,47-48H,5-10,15-22,31-42,45-46H2,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from D1 receptor from porcine cerebral cortex homogenates				J Med Chem 54: 4896-903 (2011) Article DOI: 10.1021/jm2004859 BindingDB Entry DOI: 10.7270/Q2RB74ZR
					More data for this Ligand-Target Pair