BDBM50348370 CHEMBL1800819
SMILES: COc1ccc(\C=N\NC(=O)CSc2cc(C)nc3ccccc23)cc1
InChI Key: InChIKey=OZFIUHNMJOELEE-CIAFOILYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus) | BDBM50348370 (CHEMBL1800819) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Omeros Corp. Curated by ChEMBL | Assay Description Inhibition of mouse PDE10A assessed as inhibition of hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting | Bioorg Med Chem Lett 21: 4155-9 (2011) Article DOI: 10.1016/j.bmcl.2011.05.100 BindingDB Entry DOI: 10.7270/Q2CJ8FRT | |||||||||||
More data for this Ligand-Target Pair |