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BDBM50349339 CHEMBL1809245

SMILES: NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(=O)N2CCN(Cc3ccccc3)CC2)NS(=O)(=O)Cc2ccccc2)cc1

InChI Key: InChIKey=CZAUWJFJROXMSN-JSOSNVBQSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50349339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane protease serine 11D


(Homo sapiens (Human))		BDBM50349339
PNG
(CHEMBL1809245)
Show SMILES NC(=N)c1ccc(CNC(=O)[C@@H]2CCCN2C(=O)[C@@H](CC(=O)N2CCN(Cc3ccccc3)CC2)NS(=O)(=O)Cc2ccccc2)cc1 |r|
Show InChI InChI=1S/C35H43N7O5S/c36-33(37)29-15-13-26(14-16-29)23-38-34(44)31-12-7-17-42(31)35(45)30(39-48(46,47)25-28-10-5-2-6-11-28)22-32(43)41-20-18-40(19-21-41)24-27-8-3-1-4-9-27/h1-6,8-11,13-16,30-31,39H,7,12,17-25H2,(H3,36,37)(H,38,44)/t30-,31+/m1/s1
KEGG

UniProtKB/SwissProt

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Similars
Article
PubMed
 158n/an/an/an/an/an/an/an/a



Philipps University Marburg

Curated by ChEMBL


Assay Description
Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...

Bioorg Med Chem Lett 21: 4860-4 (2011)


Article DOI: 10.1016/j.bmcl.2011.06.033
BindingDB Entry DOI: 10.7270/Q2ST7Q5M
More data for this
Ligand-Target Pair