BDBM50349492 CHEMBL1808632

SMILES: ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccncc1

InChI Key: InChIKey=BKMRGKPESUBTDU-DUXPYHPUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50349492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50349492 (CHEMBL1808632) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccncc1 Show InChI InChI=1S/C16H15N3O4S/c20-16(18-21)4-2-12-1-3-13-10-19(11-14(13)9-12)24(22,23)15-5-7-17-8-6-15/h1-9,21H,10-11H2,(H,18,20)/b4-2+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human ERG by automated patch clamp assay				Bioorg Med Chem Lett 21: 4909-12 (2011) Article DOI: 10.1016/j.bmcl.2011.06.015 BindingDB Entry DOI: 10.7270/Q2542NZQ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50349492 (CHEMBL1808632) Show SMILES ONC(=O)\C=C\c1ccc2CN(Cc2c1)S(=O)(=O)c1ccncc1 Show InChI InChI=1S/C16H15N3O4S/c20-16(18-21)4-2-12-1-3-13-10-19(11-14(13)9-12)24(22,23)15-5-7-17-8-6-15/h1-9,21H,10-11H2,(H,18,20)/b4-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of purified recombinant HDAC1				Bioorg Med Chem Lett 21: 4909-12 (2011) Article DOI: 10.1016/j.bmcl.2011.06.015 BindingDB Entry DOI: 10.7270/Q2542NZQ
					More data for this Ligand-Target Pair