Found 5 hits for monomerid = 50350386 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50350386
(CHEMBL1813478)Show SMILES CN1C[C@@H]2CCC[C@@]2(C1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2N/c1-17-8-11-3-2-6-14(11,9-17)10-4-5-12(15)13(16)7-10/h4-5,7,11H,2-3,6,8-9H2,1H3/t11-,14+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysis |
J Med Chem 54: 5283-95 (2011)
Article DOI: 10.1021/jm101312a
BindingDB Entry DOI: 10.7270/Q29K4BM0 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50350386
(CHEMBL1813478)Show SMILES CN1C[C@@H]2CCC[C@@]2(C1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2N/c1-17-8-11-3-2-6-14(11,9-17)10-4-5-12(15)13(16)7-10/h4-5,7,11H,2-3,6,8-9H2,1H3/t11-,14+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of CYP2C19 in human liver microsomes by LC-MS/MS analysis |
J Med Chem 54: 5283-95 (2011)
Article DOI: 10.1021/jm101312a
BindingDB Entry DOI: 10.7270/Q29K4BM0 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50350386
(CHEMBL1813478)Show SMILES CN1C[C@@H]2CCC[C@@]2(C1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2N/c1-17-8-11-3-2-6-14(11,9-17)10-4-5-12(15)13(16)7-10/h4-5,7,11H,2-3,6,8-9H2,1H3/t11-,14+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysis |
J Med Chem 54: 5283-95 (2011)
Article DOI: 10.1021/jm101312a
BindingDB Entry DOI: 10.7270/Q29K4BM0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50350386
(CHEMBL1813478)Show SMILES CN1C[C@@H]2CCC[C@@]2(C1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2N/c1-17-8-11-3-2-6-14(11,9-17)10-4-5-12(15)13(16)7-10/h4-5,7,11H,2-3,6,8-9H2,1H3/t11-,14+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 5.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of human ERG expressed in CHO cells by high throughput single cell planar patch clamp method |
J Med Chem 54: 5283-95 (2011)
Article DOI: 10.1021/jm101312a
BindingDB Entry DOI: 10.7270/Q29K4BM0 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50350386
(CHEMBL1813478)Show SMILES CN1C[C@@H]2CCC[C@@]2(C1)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C14H17Cl2N/c1-17-8-11-3-2-6-14(11,9-17)10-4-5-12(15)13(16)7-10/h4-5,7,11H,2-3,6,8-9H2,1H3/t11-,14+/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sunovion Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of CYP2D6 in human liver microsomes by LC-MS/MS analysis |
J Med Chem 54: 5283-95 (2011)
Article DOI: 10.1021/jm101312a
BindingDB Entry DOI: 10.7270/Q29K4BM0 |
More data for this
Ligand-Target Pair | |
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