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BDBM50353030 CHEMBL1821993

SMILES: COc1cc(cc2OCOc12)[C@@H]1O[C@H]([C@H](C)[C@H]1C)c1cc(OC)c(OC)c(OC)c1

InChI Key: InChIKey=RKSBJQZDPAGEQW-QNLIWRIUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353030   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Nitric Oxide Synthase, inducible


(Mus musculus (mouse))		BDBM50353030
PNG
(CHEMBL1821993)
Show SMILES COc1cc(cc2OCOc12)[C@@H]1O[C@H]([C@H](C)[C@H]1C)c1cc(OC)c(OC)c(OC)c1 |r|
Show InChI InChI=1S/C23H28O7/c1-12-13(2)21(15-9-18(26-5)23-19(10-15)28-11-29-23)30-20(12)14-7-16(24-3)22(27-6)17(8-14)25-4/h7-10,12-13,20-21H,11H2,1-6H3/t12-,13-,20-,21-/m1/s1
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Similars
Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibition of iNOS in mouse RAW264.7 cells assessed as anti-inflammatory activity by measuring maximum inhibition of LPS-induced nitric oxide product...

J Nat Prod 74: 1875-80 (2011)


Article DOI: 10.1021/np200279r
BindingDB Entry DOI: 10.7270/Q2474B72
More data for this
Ligand-Target Pair