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SMILES: CCC(N(CCCN)C(=O)C1COc2ccccc2O1)c1nc2ccsc2c(=O)n1Cc1ccccc1

InChI Key: InChIKey=FXIRPBZAEDIOMO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353800   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50353800
PNG
(CHEMBL1829417)
Show SMILES CCC(N(CCCN)C(=O)C1COc2ccccc2O1)c1nc2ccsc2c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C28H30N4O4S/c1-2-21(31(15-8-14-29)27(33)24-18-35-22-11-6-7-12-23(22)36-24)26-30-20-13-16-37-25(20)28(34)32(26)17-19-9-4-3-5-10-19/h3-7,9-13,16,21,24H,2,8,14-15,17-18,29H2,1H3
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Article
PubMed
n/an/a 2.31E+3n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assay

J Med Chem 54: 6734-50 (2011)


Article DOI: 10.1021/jm200629m
BindingDB Entry DOI: 10.7270/Q2ZC838Z
More data for this
Ligand-Target Pair