BDBM50355639 CHEMBL1910879

SMILES: OC(=O)c1sccc1SCc1cccc(Cl)c1Cl

InChI Key: InChIKey=IMNZYJADHDSLID-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50355639 (CHEMBL1910879) Show SMILES OC(=O)c1sccc1SCc1cccc(Cl)c1Cl Show InChI InChI=1S/C12H8Cl2O2S2/c13-8-3-1-2-7(10(8)14)6-18-9-4-5-17-11(9)12(15)16/h1-5H,6H2,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincubated...				J Med Chem 54: 6548-62 (2011) Article DOI: 10.1021/jm2003766 BindingDB Entry DOI: 10.7270/Q2862GTG
					More data for this Ligand-Target Pair
Leukocyte common antigen (Homo sapiens (Human))	BDBM50355639 (CHEMBL1910879) Show SMILES OC(=O)c1sccc1SCc1cccc(Cl)c1Cl Show InChI InChI=1S/C12H8Cl2O2S2/c13-8-3-1-2-7(10(8)14)6-18-9-4-5-17-11(9)12(15)16/h1-5H,6H2,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of CD45 expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincubated ...				J Med Chem 54: 6548-62 (2011) Article DOI: 10.1021/jm2003766 BindingDB Entry DOI: 10.7270/Q2862GTG
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase gamma (Homo sapiens (Human))	BDBM50355639 (CHEMBL1910879) Show SMILES OC(=O)c1sccc1SCc1cccc(Cl)c1Cl Show InChI InChI=1S/C12H8Cl2O2S2/c13-8-3-1-2-7(10(8)14)6-18-9-4-5-17-11(9)12(15)16/h1-5H,6H2,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of RPTPgamma expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincub...				J Med Chem 54: 6548-62 (2011) Article DOI: 10.1021/jm2003766 BindingDB Entry DOI: 10.7270/Q2862GTG
					More data for this Ligand-Target Pair