BDBM50356344 CHEMBL1911405

SMILES: OC(=O)CC1(C2CC3CC(C2)CC1C3)c1cccc(F)c1

InChI Key: InChIKey=WVDLXPCYCLQJDS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356344   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50356344 (CHEMBL1911405) Show SMILES OC(=O)CC1(C2CC3CC(C2)CC1C3)c1cccc(F)c1 |TLB:13:12:10:6.7.8,3:4:6.13.7:11.9.10,THB:13:7:4.12.11:10,8:7:4:11.9.10,8:9:4:6.13.7,3:4:10:6.7.8,14:4:6.13.7:11.9.10,(5.96,-24.19,;7.29,-24.96,;8.63,-24.19,;7.29,-26.5,;8.63,-27.28,;9.83,-26,;11.16,-26.49,;12.55,-26.15,;12.56,-24.62,;11.17,-24.04,;9.82,-24.52,;10.13,-25.28,;10.13,-26.86,;11.54,-27.43,;7.89,-28.63,;8.69,-29.94,;7.95,-31.29,;6.4,-31.33,;5.61,-30.01,;4.06,-30.04,;6.35,-28.66,)| Show InChI InChI=1S/C18H21FO2/c19-16-3-1-2-13(9-16)18(10-17(20)21)14-5-11-4-12(7-14)8-15(18)6-11/h1-3,9,11-12,14-15H,4-8,10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50356344 (CHEMBL1911405) Show SMILES OC(=O)CC1(C2CC3CC(C2)CC1C3)c1cccc(F)c1 |TLB:13:12:10:6.7.8,3:4:6.13.7:11.9.10,THB:13:7:4.12.11:10,8:7:4:11.9.10,8:9:4:6.13.7,3:4:10:6.7.8,14:4:6.13.7:11.9.10,(5.96,-24.19,;7.29,-24.96,;8.63,-24.19,;7.29,-26.5,;8.63,-27.28,;9.83,-26,;11.16,-26.49,;12.55,-26.15,;12.56,-24.62,;11.17,-24.04,;9.82,-24.52,;10.13,-25.28,;10.13,-26.86,;11.54,-27.43,;7.89,-28.63,;8.69,-29.94,;7.95,-31.29,;6.4,-31.33,;5.61,-30.01,;4.06,-30.04,;6.35,-28.66,)| Show InChI InChI=1S/C18H21FO2/c19-16-3-1-2-13(9-16)18(10-17(20)21)14-5-11-4-12(7-14)8-15(18)6-11/h1-3,9,11-12,14-15H,4-8,10H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD-1				Bioorg Med Chem Lett 21: 6699-704 (2011) Article DOI: 10.1016/j.bmcl.2011.09.055 BindingDB Entry DOI: 10.7270/Q2Q240NV
					More data for this Ligand-Target Pair