BDBM50356454 CHEMBL1911687

SMILES: Clc1ccccc1Sc1[nH]c(=O)c(C#N)c2CCCCc12

InChI Key: InChIKey=LAMKXQNYFVTWQP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50356454 (CHEMBL1911687) Show SMILES Clc1ccccc1Sc1[nH]c(=O)c(C#N)c2CCCCc12 Show InChI InChI=1S/C16H13ClN2OS/c17-13-7-3-4-8-14(13)21-16-11-6-2-1-5-10(11)12(9-18)15(20)19-16/h3-4,7-8H,1-2,5-6H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 21: 6693-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.058 BindingDB Entry DOI: 10.7270/Q2FN16M4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50356454 (CHEMBL1911687) Show SMILES Clc1ccccc1Sc1[nH]c(=O)c(C#N)c2CCCCc12 Show InChI InChI=1S/C16H13ClN2OS/c17-13-7-3-4-8-14(13)21-16-11-6-2-1-5-10(11)12(9-18)15(20)19-16/h3-4,7-8H,1-2,5-6H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation plate reader				Bioorg Med Chem Lett 21: 6693-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.058 BindingDB Entry DOI: 10.7270/Q2FN16M4
					More data for this Ligand-Target Pair