BDBM50358288 CHEMBL1922404

SMILES: Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1

InChI Key: InChIKey=IINJMWYMLCBENL-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50358288   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50358288 (CHEMBL1922404) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of RON				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50358288 (CHEMBL1922404) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant c-met by HTRF assay				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50358288 (CHEMBL1922404) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of AurA				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50358288 (CHEMBL1922404) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of TRKA				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50358288 (CHEMBL1922404) Show SMILES Cn1cc(cn1)-c1ccc2nnc(Cc3cccc4c3cc[nH]c4=O)n2n1 Show InChI InChI=1S/C19H15N7O/c1-25-11-13(10-21-25)16-5-6-17-22-23-18(26(17)24-16)9-12-3-2-4-15-14(12)7-8-20-19(15)27/h2-8,10-11H,9H2,1H3,(H,20,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of FLT3				Bioorg Med Chem Lett 21: 7185-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.066 BindingDB Entry DOI: 10.7270/Q24Q7VDG
					More data for this Ligand-Target Pair