BDBM50358555 CHEMBL1923554

SMILES: CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC(C)(C)[C@H](N)C(=O)N[C@@H](CO)C(O)=O)OC(=O)CCCCCCCCCCCCCCC

InChI Key: InChIKey=OWUGZJJNOSYSTR-RRRSLPDISA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 2 (TLR2) (Homo sapiens (Human))	BDBM50358555 (CHEMBL1923554) Show SMILES CCCCCCCCCCCCCCCC(=O)OC[C@H](CSC(C)(C)[C@H](N)C(=O)N[C@@H](CO)C(O)=O)OC(=O)CCCCCCCCCCCCCCC |r| Show InChI InChI=1S/C43H82N2O8S/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(47)52-34-36(35-54-43(3,4)40(44)41(49)45-37(33-46)42(50)51)53-39(48)32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h36-37,40,46H,5-35,44H2,1-4H3,(H,45,49)(H,50,51)/t36-,37+,40-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR2 expressed in HEK293 cells assessed as NF-kappaB induction measured soluble alkaline phosphatase after 12 hrs by spectr...				J Med Chem 54: 8148-60 (2011) Article DOI: 10.1021/jm201071e BindingDB Entry DOI: 10.7270/Q2KP82K8
					More data for this Ligand-Target Pair