null

SMILES: CCCC(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc(OC)c(c1)C(F)(F)F

InChI Key: InChIKey=HYNCRNBGXDRESJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM50358824 (CHEMBL1922925) Show SMILES CCCC(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc(OC)c(c1)C(F)(F)F Show InChI InChI=1S/C32H30ClF3N2O5/c1-3-4-21(15-19-5-7-20(8-6-19)31(42)37-14-13-29(39)40)30(41)27-17-22-16-23(33)9-11-26(22)38(27)24-10-12-28(43-2)25(18-24)32(34,35)36/h5-12,16-18,21H,3-4,13-15H2,1-2H3,(H,37,42)(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-glucagon from human glucagon receptor expressed in CHO cells after 4 to 12 hrs by scintillation proximity assay				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50358824 (CHEMBL1922925) Show SMILES CCCC(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc(OC)c(c1)C(F)(F)F Show InChI InChI=1S/C32H30ClF3N2O5/c1-3-4-21(15-19-5-7-20(8-6-19)31(42)37-14-13-29(39)40)30(41)27-17-22-16-23(33)9-11-26(22)38(27)24-10-12-28(43-2)25(18-24)32(34,35)36/h5-12,16-18,21H,3-4,13-15H2,1-2H3,(H,37,42)(H,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human glucagon receptor expressed in CHO cells assessed as inhibition of forskolin/glucagon-induced cAMP production preincubat...				Bioorg Med Chem Lett 21: 7124-30 (2011) Article DOI: 10.1016/j.bmcl.2011.09.105 BindingDB Entry DOI: 10.7270/Q2HT2PRF
					More data for this Ligand-Target Pair