BDBM50358846 CHEMBL1923431

SMILES: Cc1[nH]c(C(=O)NC2CCN(CC2)c2cc(cc(Cl)n2)C(N)=O)c(Cl)c1Cl

InChI Key: InChIKey=DDZQOAWVENUEIU-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50358846 (CHEMBL1923431) Show SMILES Cc1[nH]c(C(=O)NC2CCN(CC2)c2cc(cc(Cl)n2)C(N)=O)c(Cl)c1Cl Show InChI InChI=1S/C17H18Cl3N5O2/c1-8-13(19)14(20)15(22-8)17(27)23-10-2-4-25(5-3-10)12-7-9(16(21)26)6-11(18)24-12/h6-7,10,22H,2-5H2,1H3,(H2,21,26)(H,23,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Boston Curated by ChEMBL					Assay Description Inhibition of ATPase activity of recombinant Staphylococcus aureus DNA gyrase B hybrid tetramer enzyme reconstituted from Escherichia coli GyrA by am...				Bioorg Med Chem Lett 21: 7416-20 (2011) Article DOI: 10.1016/j.bmcl.2011.10.010 BindingDB Entry DOI: 10.7270/Q2RB7512
					More data for this Ligand-Target Pair				3D Structure (crystal)