BDBM50359970 CHEMBL1927262

SMILES: Cc1ccc(F)cc1-c1nc2[nH]nc(N)c2c2CCCCc12

InChI Key: InChIKey=YPULTKAHHAYKOE-UHFFFAOYSA-N

Data: 1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-A receptor 4 (Homo sapiens (Human))	BDBM50359970 (CHEMBL1927262) Show SMILES Cc1ccc(F)cc1-c1nc2[nH]nc(N)c2c2CCCCc12 Show InChI InChI=1S/C17H17FN4/c1-9-6-7-10(18)8-13(9)15-12-5-3-2-4-11(12)14-16(19)21-22-17(14)20-15/h6-8H,2-5H2,1H3,(H3,19,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
VU University Amsterdam Curated by ChEMBL					Assay Description Inhibition of his-tagged EPHA4-mediated poly(Glu,Tyr) phosphorylation after 75 mins using E4:Y1 as substrate by fluorescence assay				Eur J Med Chem 47: 493-500 (2012) Article DOI: 10.1016/j.ejmech.2011.11.020 BindingDB Entry DOI: 10.7270/Q26110R2
					More data for this Ligand-Target Pair				3D Structure (crystal)