BDBM50360001 CHEMBL1928322

SMILES: Cc1cccc2cnn(CC3=NCCN3)c12

InChI Key: InChIKey=CHIFEYGVHJOXNJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50360001   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Imidazoline I1 (RAT)	BDBM50360001 (CHEMBL1928322) Show SMILES Cc1cccc2cnn(CC3=NCCN3)c12 |t:10| Show InChI InChI=1S/C12H14N4/c1-9-3-2-4-10-7-15-16(12(9)10)8-11-13-5-6-14-11/h2-4,7H,5-6,8H2,1H3,(H,13,14)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Displacement of [3H]clonidine from imidazoline I1 receptor in Sprague-Dawley rat kidney membranes after 45 mins by scintillation counting				Bioorg Med Chem 20: 108-16 (2011) Article DOI: 10.1016/j.bmc.2011.11.025 BindingDB Entry DOI: 10.7270/Q2DJ5G10
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50360001 (CHEMBL1928322) Show SMILES Cc1cccc2cnn(CC3=NCCN3)c12 |t:10| Show InChI InChI=1S/C12H14N4/c1-9-3-2-4-10-7-15-16(12(9)10)8-11-13-5-6-14-11/h2-4,7H,5-6,8H2,1H3,(H,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a
Medical University of Gdansk Curated by ChEMBL					Assay Description Agonist activity at human adrenoceptor alpha2A expressed in CHOK1 cells assessed as stimulation of agonist-induced [35S]GTPgammaS binding by scintill...				Bioorg Med Chem 20: 108-16 (2011) Article DOI: 10.1016/j.bmc.2011.11.025 BindingDB Entry DOI: 10.7270/Q2DJ5G10
					More data for this Ligand-Target Pair