BDBM50360612 CHEMBL1933541

SMILES: CCN1CCCC(C1)N1CC[C@@]2(C1)CN(C(=O)c1cc3cc(F)ccc3[nH]1)c1ccccc21

InChI Key: InChIKey=IQJWKDBLIXZGGV-IAIRZMIISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Syk protein (Mus musculus)	BDBM50360612 (CHEMBL1933541) Show SMILES CCN1CCCC(C1)N1CC[C@@]2(C1)CN(C(=O)c1cc3cc(F)ccc3[nH]1)c1ccccc21 |r| Show InChI InChI=1S/C27H31FN4O/c1-2-30-12-5-6-21(16-30)31-13-11-27(17-31)18-32(25-8-4-3-7-22(25)27)26(33)24-15-19-14-20(28)9-10-23(19)29-24/h3-4,7-10,14-15,21,29H,2,5-6,11-13,16-18H2,1H3/t21?,27-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA				Bioorg Med Chem Lett 22: 190-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.036 BindingDB Entry DOI: 10.7270/Q2CF9QJS
					More data for this Ligand-Target Pair