BDBM50361340 CHEMBL1933822
SMILES: CCCCCS(=O)(=O)NC(=O)CCc1cc(OC(C)C)nn1Cc1ccc(cc1Cl)C(F)(F)F
InChI Key: InChIKey=HDOPACYQZJBICA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50361340 (CHEMBL1933822) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd Curated by ChEMBL | Assay Description Displacement of [3H]-AD-5061 from human GST-tagged PPARgamma | Bioorg Med Chem 20: 714-33 (2012) Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50361340 (CHEMBL1933822) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd Curated by ChEMBL | Assay Description Agonist activity at full length human PPARgamma1 transfected in human CHOK1 cells co expressing RXRalpha and PPRE after 1 day by luciferase reporter ... | Bioorg Med Chem 20: 714-33 (2012) Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50361340 (CHEMBL1933822) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha expressed in COS-1 cells after 1 day by luciferase reporter gene transactivation assay | Bioorg Med Chem 20: 714-33 (2012) Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50361340 (CHEMBL1933822) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Ltd Curated by ChEMBL | Assay Description Agonist activity at human PPARdelta expressed in COS-1 cells after 2 days by luciferase reporter gene transactivation assay | Bioorg Med Chem 20: 714-33 (2012) Article DOI: 10.1016/j.bmc.2011.12.008 BindingDB Entry DOI: 10.7270/Q2PK0GK3 | |||||||||||
More data for this Ligand-Target Pair |