Found 3 hits for monomerid = 50362147 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Apoptosis regulator Bcl-2
(Homo sapiens (Human)) | BDBM50362147
(CHEMBL1940666)Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O |r| Show InChI InChI=1S/C34H32N6O7S2/c1-22(41)37-31(19-24-21-36-29-10-6-5-9-28(24)29)34(43)38-25-13-11-23(12-14-25)33(42)39-49(46,47)27-15-16-30(32(20-27)40(44)45)35-17-18-48-26-7-3-2-4-8-26/h2-16,20-21,31,35-36H,17-19H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t31-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 830 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to Bcl-2 by competitive fluorescence polarization assay |
Bioorg Med Chem Lett 22: 39-44 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.101
BindingDB Entry DOI: 10.7270/Q2MG7PX2 |
More data for this
Ligand-Target Pair | |
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human)) | BDBM50362147
(CHEMBL1940666)Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O |r| Show InChI InChI=1S/C34H32N6O7S2/c1-22(41)37-31(19-24-21-36-29-10-6-5-9-28(24)29)34(43)38-25-13-11-23(12-14-25)33(42)39-49(46,47)27-15-16-30(32(20-27)40(44)45)35-17-18-48-26-7-3-2-4-8-26/h2-16,20-21,31,35-36H,17-19H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t31-/m0/s1 | PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to Mcl-1 by competitive fluorescence polarization assay |
Bioorg Med Chem Lett 22: 39-44 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.101
BindingDB Entry DOI: 10.7270/Q2MG7PX2 |
More data for this
Ligand-Target Pair | |
Bcl-2-like protein 1
(Homo sapiens (Human)) | BDBM50362147
(CHEMBL1940666)Show SMILES CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O |r| Show InChI InChI=1S/C34H32N6O7S2/c1-22(41)37-31(19-24-21-36-29-10-6-5-9-28(24)29)34(43)38-25-13-11-23(12-14-25)33(42)39-49(46,47)27-15-16-30(32(20-27)40(44)45)35-17-18-48-26-7-3-2-4-8-26/h2-16,20-21,31,35-36H,17-19H2,1H3,(H,37,41)(H,38,43)(H,39,42)/t31-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Binding affinity to Bcl-xL by competitive fluorescence polarization assay |
Bioorg Med Chem Lett 22: 39-44 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.101
BindingDB Entry DOI: 10.7270/Q2MG7PX2 |
More data for this
Ligand-Target Pair | |
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