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SMILES: COc1ccc2C(CCCc2c1)NC(=O)C[C@H]1N(C=CNC1=O)S(=O)(=O)c1ccc(C)cc1

InChI Key: InChIKey=XPRAJGHGQLOJGP-FOIFJWKZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362356   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM50362356
PNG
(CHEMBL1939765)
Show SMILES COc1ccc2C(CCCc2c1)NC(=O)C[C@H]1N(C=CNC1=O)S(=O)(=O)c1ccc(C)cc1 |r,c:20|
Show InChI InChI=1S/C24H27N3O5S/c1-16-6-9-19(10-7-16)33(30,31)27-13-12-25-24(29)22(27)15-23(28)26-21-5-3-4-17-14-18(32-2)8-11-20(17)21/h6-14,21-22H,3-5,15H2,1-2H3,(H,25,29)(H,26,28)/t21?,22-/m1/s1
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KEGG

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 8.95n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...

Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair