BDBM50362940 CHEMBL1946263

SMILES: Nc1nc2ccc(cc2[nH]1)-c1cnc2[nH]c(=O)n(CC3CCOCC3)c2n1

InChI Key: InChIKey=CKKDKSVJTIVOCY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50362940 (CHEMBL1946263) Show SMILES Nc1nc2ccc(cc2[nH]1)-c1cnc2[nH]c(=O)n(CC3CCOCC3)c2n1 Show InChI InChI=1S/C18H19N7O2/c19-17-22-12-2-1-11(7-13(12)23-17)14-8-20-15-16(21-14)25(18(26)24-15)9-10-3-5-27-6-4-10/h1-2,7-8,10H,3-6,9H2,(H3,19,22,23)(H,20,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 21: 6793-9 (2011) Article DOI: 10.1016/j.bmcl.2011.09.035 BindingDB Entry DOI: 10.7270/Q28W3DR1
					More data for this Ligand-Target Pair