BDBM50364106 CHEMBL1950957

SMILES: CN1Cc2cc(ccc2N(C)C1=O)S(=O)(=O)N1CCOCC1

InChI Key: InChIKey=LFBDSGLXLXJATE-UHFFFAOYSA-N

Data: 3 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50364106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 2 (Homo sapiens (Human))	BDBM50364106 (CHEMBL1950957) Show SMILES CN1Cc2cc(ccc2N(C)C1=O)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C14H19N3O4S/c1-15-10-11-9-12(3-4-13(11)16(2)14(15)18)22(19,20)17-5-7-21-8-6-17/h3-4,9H,5-8,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of His-6 tagged BRD2 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis				J Med Chem 55: 576-86 (2012) Article DOI: 10.1021/jm201320w BindingDB Entry DOI: 10.7270/Q2F47PM1
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50364106 (CHEMBL1950957) Show SMILES CN1Cc2cc(ccc2N(C)C1=O)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C14H19N3O4S/c1-15-10-11-9-12(3-4-13(11)16(2)14(15)18)22(19,20)17-5-7-21-8-6-17/h3-4,9H,5-8,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of His-6 tagged BRD4 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis				J Med Chem 55: 576-86 (2012) Article DOI: 10.1021/jm201320w BindingDB Entry DOI: 10.7270/Q2F47PM1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 3 (Homo sapiens (Human))	BDBM50364106 (CHEMBL1950957) Show SMILES CN1Cc2cc(ccc2N(C)C1=O)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C14H19N3O4S/c1-15-10-11-9-12(3-4-13(11)16(2)14(15)18)22(19,20)17-5-7-21-8-6-17/h3-4,9H,5-8,10H2,1-2H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline R&D Curated by ChEMBL					Assay Description Inhibition of His-6 tagged BRD3 expressed in Escherichia coli after 60 mins by fluorescence anisotropic analysis				J Med Chem 55: 576-86 (2012) Article DOI: 10.1021/jm201320w BindingDB Entry DOI: 10.7270/Q2F47PM1
					More data for this Ligand-Target Pair