null
SMILES: CN(C(=O)N1CC(C1)OC(c1ccc(Cl)cc1)c1cccnc1Cl)c1ccccc1
InChI Key: InChIKey=GPUDKIUSSXZVNS-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat)) | BDBM50364272 (CHEMBL1952270) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd Curated by ChEMBL | Assay Description Inhibition of rat FAAH using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetry | Bioorg Med Chem Lett 22: 901-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.032 BindingDB Entry DOI: 10.7270/Q2D79BVH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50364272 (CHEMBL1952270) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.93E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd Curated by ChEMBL | Assay Description Inhibition of human FAAH expressed in CHO cells using 7-amino-4-methylcoumarine amide as substrate preincubated for 1 hr by fluorimetry | Bioorg Med Chem Lett 22: 901-6 (2012) Article DOI: 10.1016/j.bmcl.2011.12.032 BindingDB Entry DOI: 10.7270/Q2D79BVH | |||||||||||
More data for this Ligand-Target Pair |