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BDBM50365824 CHEMBL1957003

SMILES: CC(C)N1CCC[C@H](Cn2c(C)nc3cnc(Oc4ccc5n(C)cnc5c4)cc3c2=O)C1

InChI Key: InChIKey=FRGRMZRHUBDUDQ-SFHVURJKSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50365824   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ghrelin receptor


(Homo sapiens (Human))		BDBM50365824
PNG
(CHEMBL1957003)
Show SMILES CC(C)N1CCC[C@H](Cn2c(C)nc3cnc(Oc4ccc5n(C)cnc5c4)cc3c2=O)C1 |r|
Show InChI InChI=1S/C25H30N6O2/c1-16(2)30-9-5-6-18(13-30)14-31-17(3)28-22-12-26-24(11-20(22)25(31)32)33-19-7-8-23-21(10-19)27-15-29(23)4/h7-8,10-12,15-16,18H,5-6,9,13-14H2,1-4H3/t18-/m0/s1
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Similars
Article
PubMed
 0.5n/an/an/an/an/an/an/an/a



Prosidion Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]-Ghrelin from human GHSR membranes overexpressing GSH-R1a by scintillation counting

Bioorg Med Chem Lett 22: 2271-8 (2012)


Article DOI: 10.1016/j.bmcl.2012.01.078
BindingDB Entry DOI: 10.7270/Q20G3KMP
More data for this
Ligand-Target Pair