BDBM50367443 CHEMBL45778

SMILES: CCCCN1CCC[C@@H](C1)c1cccc(O)c1

InChI Key: InChIKey=ITXBDHMIXPKNIE-AWEZNQCLSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50367443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367443 (CHEMBL45778) Show SMILES CCCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of spiperone from dopamine receptor D2 of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367443 (CHEMBL45778) Show SMILES CCCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description In vitro for binding affinity against sigma receptor using [3H](+)-3-PPP as radioligand				J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50367443 (CHEMBL45778) Show SMILES CCCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of G£teborg Curated by ChEMBL					Assay Description Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand				J Med Chem 30: 2169-74 (1988) BindingDB Entry DOI: 10.7270/Q2MW2HQJ
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50367443 (CHEMBL45778) Show SMILES CCCCN1CCC[C@@H](C1)c1cccc(O)c1 Show InChI InChI=1S/C15H23NO/c1-2-3-9-16-10-5-7-14(12-16)13-6-4-8-15(17)11-13/h4,6,8,11,14,17H,2-3,5,7,9-10,12H2,1H3/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of (+)-3PPP from sigma receptor of rat brain membrane				J Med Chem 37: 1727-32 (1994) Checked by Author BindingDB Entry DOI: 10.7270/Q25B0408
					More data for this Ligand-Target Pair