BDBM50368324 CHEMBL1744091

SMILES: OC(=O)C[C@]1(O)C[C@H](Oc2ccc(F)cc12)C(=O)c1ccccc1

InChI Key: InChIKey=JWMBKEOUJOXUAH-MAUKXSAKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50368324 (CHEMBL1744091) Show SMILES OC(=O)C[C@]1(O)C[C@H](Oc2ccc(F)cc12)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C18H15FO5/c19-12-6-7-14-13(8-12)18(23,10-16(20)21)9-15(24-14)17(22)11-4-2-1-3-5-11/h1-8,15,23H,9-10H2,(H,20,21)/t15-,18+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human placental aldose reductase				J Med Chem 35: 2169-77 (1992) BindingDB Entry DOI: 10.7270/Q2833SN9
					More data for this Ligand-Target Pair