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SMILES: Fc1ccc(cc1)C(=O)C1CCN(CCNC(=O)Nc2ccccc2)CC1

InChI Key: InChIKey=PUIYSHDOKUSUEM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50368521   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2A/2B/2C


(Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)		BDBM50368521
PNG
(CHEMBL1202028)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCNC(=O)Nc2ccccc2)CC1
Show InChI InChI=1S/C21H24FN3O2/c22-18-8-6-16(7-9-18)20(26)17-10-13-25(14-11-17)15-12-23-21(27)24-19-4-2-1-3-5-19/h1-9,17H,10-15H2,(H2,23,24,27)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 4.30n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 2 receptor in rat using [3H]ketanserin as radioligand

J Med Chem 35: 4903-10 (1993)


BindingDB Entry DOI: 10.7270/Q26T0N86
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Rattus norvegicus (Rat))		BDBM50368521
PNG
(CHEMBL1202028)
Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCNC(=O)Nc2ccccc2)CC1
Show InChI InChI=1S/C21H24FN3O2/c22-18-8-6-16(7-9-18)20(26)17-10-13-25(14-11-17)15-12-23-21(27)24-19-4-2-1-3-5-19/h1-9,17H,10-15H2,(H2,23,24,27)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 200n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 1C receptor in rat using [3H]mesulergine as radioligand

J Med Chem 35: 4903-10 (1993)


BindingDB Entry DOI: 10.7270/Q26T0N86
More data for this
Ligand-Target Pair