BDBM50370483 CHEMBL607903

SMILES: CN1CN(C2O[C@H](CO)[C@@H](O)[C@H]2O)C2=NC=NC(O)C12

InChI Key: InChIKey=PGGFFMZKRBRMSA-IOMWUIDWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370483   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic translation initiation factor 4E (eIF4E) (Homo sapiens (Human))	BDBM50370483 (CHEMBL607903) Show SMILES CN1CN(C2O[C@H](CO)[C@@H](O)[C@H]2O)C2=NC=NC(O)C12 |r,c:16,t:14| Show InChI InChI=1S/C11H18N4O5/c1-14-4-15(9-6(14)10(19)13-3-12-9)11-8(18)7(17)5(2-16)20-11/h3,5-8,10-11,16-19H,2,4H2,1H3/t5-,6?,7-,8-,10?,11?/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory concentration against 7-methyl-GTP binding to eukaryotic translation initiation factor 4E				Bioorg Med Chem Lett 15: 2177-80 (2005) Article DOI: 10.1016/j.bmcl.2005.01.080 BindingDB Entry DOI: 10.7270/Q27D2VWP
					More data for this Ligand-Target Pair