Found 5 hits for monomerid = 50372295 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at human recombinant histamine H3 receptor expressed in HEK cells |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity at rat recombinant histamine H3 receptor in rat cortical membranes |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Antagonist activity at histamine H1 receptor by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H2 Receptor
(Homo sapiens (Human)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Antagonist activity at histamine H2 receptor by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |
Histamine H4 receptor
(Homo sapiens (Human)) | BDBM50372295
(CHEMBL429914)Show InChI InChI=1S/C20H25NO/c1-17-6-5-14-21(17)15-13-18-9-11-20(12-10-18)22-16-19-7-3-2-4-8-19/h2-4,7-12,17H,5-6,13-16H2,1H3/t17-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Antagonist activity at histamine H4 receptor by [35S]GTP-gamma-S binding assay |
Bioorg Med Chem Lett 18: 355-9 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.067 BindingDB Entry DOI: 10.7270/Q2VM4D4V |
More data for this Ligand-Target Pair | |