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SMILES: COc1cccc(c1)[C@@H]1CN(C[C@H]1C(=O)N1CCN(CC1)c1c(F)cccc1[C@@H](NC(=O)CCN(C)C)C(C)C)C(C)C

InChI Key: InChIKey=KEVDDJINAKGHQN-LBRLCBGXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50373506   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50373506
PNG
(CHEMBL272088)
Show SMILES COc1cccc(c1)[C@@H]1CN(C[C@H]1C(=O)N1CCN(CC1)c1c(F)cccc1[C@@H](NC(=O)CCN(C)C)C(C)C)C(C)C
Show InChI InChI=1S/C34H50FN5O3/c1-23(2)32(36-31(41)14-15-37(5)6)27-12-9-13-30(35)33(27)38-16-18-39(19-17-38)34(42)29-22-40(24(3)4)21-28(29)25-10-8-11-26(20-25)43-7/h8-13,20,23-24,28-29,32H,14-19,21-22H2,1-7H3,(H,36,41)/t28-,29+,32-/m0/s1
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KEGG

UniProtKB/SwissProt

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PC sid
UniChem

Similars
Article
PubMed
 3.70E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4 receptor expressed in HEK293 cells

Bioorg Med Chem Lett 18: 129-36 (2008)


Article DOI: 10.1016/j.bmcl.2007.10.115
BindingDB Entry DOI: 10.7270/Q2MK6DR5
More data for this
Ligand-Target Pair