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SMILES: Cc1cc(cc(C)c1C=Cc1cncc(c1)-c1nnn[nH]1)-c1cccnc1

InChI Key: InChIKey=XISWHAJPBGFBAF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375255   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAF proto-oncogene serine/threonine-protein kinase


(Homo sapiens (Human))		BDBM50375255
PNG
(CHEMBL374647)
Show SMILES Cc1cc(cc(C)c1C=Cc1cncc(c1)-c1nnn[nH]1)-c1cccnc1 |w:9.10|
Show InChI InChI=1S/C21H18N6/c1-14-8-18(17-4-3-7-22-12-17)9-15(2)20(14)6-5-16-10-19(13-23-11-16)21-24-26-27-25-21/h3-13H,1-2H3,(H,24,25,26,27)
PDB
MMDB

NCI pathway
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 630n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of Raf1 kinase

Bioorg Med Chem Lett 18: 2346-50 (2008)


Article DOI: 10.1016/j.bmcl.2008.02.068
BindingDB Entry DOI: 10.7270/Q25X29S8
More data for this
Ligand-Target Pair