BDBM50375371 CHEMBL412273

SMILES: COc1cc(Nc2nn3c(N[C@@H](C)CO)cc(C)nc3c2C(N)=O)cc(OC)c1

InChI Key: InChIKey=OAVUCEMQOYBXFV-NSHDSACASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50375371 (CHEMBL412273) Show SMILES COc1cc(Nc2nn3c(N[C@@H](C)CO)cc(C)nc3c2C(N)=O)cc(OC)c1 Show InChI InChI=1S/C19H24N6O4/c1-10-5-15(21-11(2)9-26)25-19(22-10)16(17(20)27)18(24-25)23-12-6-13(28-3)8-14(7-12)29-4/h5-8,11,21,26H,9H2,1-4H3,(H2,20,27)(H,23,24)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Inhibition of human cSrc				Bioorg Med Chem 16: 909-21 (2008) Article DOI: 10.1016/j.bmc.2007.10.068 BindingDB Entry DOI: 10.7270/Q2CF9R01
					More data for this Ligand-Target Pair