BDBM50376015 CHEMBL271414

SMILES: COc1cc2nccc(N(C)c3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC

InChI Key: InChIKey=XGTBKSVZQRIRGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50376015 (CHEMBL271414) Show SMILES COc1cc2nccc(N(C)c3ccc4c(cccc4c3)C(=O)Nc3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C29H24ClN3O3/c1-33(26-13-14-31-25-17-28(36-3)27(35-2)16-24(25)26)21-11-12-22-18(15-21)5-4-6-23(22)29(34)32-20-9-7-19(30)8-10-20/h4-17H,1-3H3,(H,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of KDR by HTRF assay				J Med Chem 51: 1649-67 (2008) Article DOI: 10.1021/jm701097z BindingDB Entry DOI: 10.7270/Q29C6Z8N
					More data for this Ligand-Target Pair