null

SMILES: C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key: InChIKey=MNBKMSPJQUFUAP-CDDJKKQXSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50376375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50376375 (CHEMBL412256) Show SMILES C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 Show InChI InChI=1S/C11H20N2O7S/c1-6-17-7-4-16-11(5-13-21(12,14)15)9(8(7)18-6)19-10(2,3)20-11/h6-9,13H,4-5H2,1-3H3,(H2,12,14,15)/t6-,7-,8-,9+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by 4-NPA hydrolysis assay				J Med Chem 51: 2518-21 (2008) Article DOI: 10.1021/jm7015649 BindingDB Entry DOI: 10.7270/Q22R3SJN
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50376375 (CHEMBL412256) Show SMILES C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 Show InChI InChI=1S/C11H20N2O7S/c1-6-17-7-4-16-11(5-13-21(12,14)15)9(8(7)18-6)19-10(2,3)20-11/h6-9,13H,4-5H2,1-3H3,(H2,12,14,15)/t6-,7-,8-,9+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	7.0	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human carbonic anhydrase 2 in presence of 10 mM PIPES and 200 uM NaCl at pH 7.0 by ThermoFluor method				J Med Chem 51: 2518-21 (2008) Article DOI: 10.1021/jm7015649 BindingDB Entry DOI: 10.7270/Q22R3SJN
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50376375 (CHEMBL412256) Show SMILES C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 Show InChI InChI=1S/C11H20N2O7S/c1-6-17-7-4-16-11(5-13-21(12,14)15)9(8(7)18-6)19-10(2,3)20-11/h6-9,13H,4-5H2,1-3H3,(H2,12,14,15)/t6-,7-,8-,9+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>5.70E+4	n/a	n/a	n/a	7.0	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human carbonic anhydrase 2 in presence of 10 mM PIPES and 100 uM Na2SO4 at pH 7.0 by ThermoFluor method				J Med Chem 51: 2518-21 (2008) Article DOI: 10.1021/jm7015649 BindingDB Entry DOI: 10.7270/Q22R3SJN
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50376375 (CHEMBL412256) Show SMILES C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 Show InChI InChI=1S/C11H20N2O7S/c1-6-17-7-4-16-11(5-13-21(12,14)15)9(8(7)18-6)19-10(2,3)20-11/h6-9,13H,4-5H2,1-3H3,(H2,12,14,15)/t6-,7-,8-,9+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3.30E+4	n/a	n/a	n/a	7.0	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human carbonic anhydrase 2 in presence of 10 mM PIPES without Na+ at pH 7.0 by ThermoFluor method				J Med Chem 51: 2518-21 (2008) Article DOI: 10.1021/jm7015649 BindingDB Entry DOI: 10.7270/Q22R3SJN
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50376375 (CHEMBL412256) Show SMILES C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 Show InChI InChI=1S/C11H20N2O7S/c1-6-17-7-4-16-11(5-13-21(12,14)15)9(8(7)18-6)19-10(2,3)20-11/h6-9,13H,4-5H2,1-3H3,(H2,12,14,15)/t6-,7-,8-,9+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>5.70E+4	n/a	n/a	n/a	7.5	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human carbonic anhydrase 2 in presence of 10 mM HEPES and 100 uM Na2SO4 at pH 7.5 by ThermoFluor method				J Med Chem 51: 2518-21 (2008) Article DOI: 10.1021/jm7015649 BindingDB Entry DOI: 10.7270/Q22R3SJN
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50376375 (CHEMBL412256) Show SMILES C[C@@H]1O[C@@H]2CO[C@@]3(CNS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1 Show InChI InChI=1S/C11H20N2O7S/c1-6-17-7-4-16-11(5-13-21(12,14)15)9(8(7)18-6)19-10(2,3)20-11/h6-9,13H,4-5H2,1-3H3,(H2,12,14,15)/t6-,7-,8-,9+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	>5.70E+4	n/a	n/a	n/a	7.5	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human carbonic anhydrase 2 in presence of 10 mM HEPES without Na+ at pH 7.5 by ThermoFluor method				J Med Chem 51: 2518-21 (2008) Article DOI: 10.1021/jm7015649 BindingDB Entry DOI: 10.7270/Q22R3SJN
					More data for this Ligand-Target Pair