null

SMILES: OC(=O)c1ccccc1NC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1

InChI Key: InChIKey=YPAJYCVUCIUYLQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50376420   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor V (Homo sapiens (Human))	BDBM50376420 (CHEMBL1162110) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C22H16Cl2N2O5/c23-14-7-10-19(17(24)11-14)31-12-20(27)25-15-8-5-13(6-9-15)21(28)26-18-4-2-1-3-16(18)22(29)30/h1-11H,12H2,(H,25,27)(H,26,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Maastricht University Curated by ChEMBL					Assay Description Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assay				Proc Natl Acad Sci USA 104: 12697-702 (2007) Article DOI: 10.1073/pnas.0701051104 BindingDB Entry DOI: 10.7270/Q2F190MG
					More data for this Ligand-Target Pair
Coagulation factor V (Homo sapiens (Human))	BDBM50376420 (CHEMBL1162110) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C22H16Cl2N2O5/c23-14-7-10-19(17(24)11-14)31-12-20(27)25-15-8-5-13(6-9-15)21(28)26-18-4-2-1-3-16(18)22(29)30/h1-11H,12H2,(H,25,27)(H,26,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Maastricht University Curated by ChEMBL					Assay Description Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assay				Proc Natl Acad Sci USA 104: 12697-702 (2007) Article DOI: 10.1073/pnas.0701051104 BindingDB Entry DOI: 10.7270/Q2F190MG
					More data for this Ligand-Target Pair
Coagulation factor V (Homo sapiens (Human))	BDBM50376420 (CHEMBL1162110) Show SMILES OC(=O)c1ccccc1NC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C22H16Cl2N2O5/c23-14-7-10-19(17(24)11-14)31-12-20(27)25-15-8-5-13(6-9-15)21(28)26-18-4-2-1-3-16(18)22(29)30/h1-11H,12H2,(H,25,27)(H,26,28)(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Maastricht University Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assay				Proc Natl Acad Sci USA 104: 12697-702 (2007) Article DOI: 10.1073/pnas.0701051104 BindingDB Entry DOI: 10.7270/Q2F190MG
					More data for this Ligand-Target Pair