null
SMILES: OC(=O)COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1)-c1csnn1)Cc1ccc(NC(=O)C(O)=O)c(c1)C(O)=O
InChI Key: InChIKey=CJINCZOBTJIWBI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human)) | BDBM50376607 (CHEMBL445680) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Affymax, Inc. Curated by ChEMBL | Assay Description Inhibition of PTP1B | Bioorg Med Chem Lett 18: 2719-24 (2008) Article DOI: 10.1016/j.bmcl.2008.03.007 BindingDB Entry DOI: 10.7270/Q23J3DTX | |||||||||||
More data for this Ligand-Target Pair |