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BDBM50376796 CHEMBL260824

SMILES: CCN(Cc1ccccc1)C1CCCc2nc(cc(CC)c12)-c1c(CC)cccc1CC

InChI Key: InChIKey=KPVVYLNLPPTVJX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376796   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))		BDBM50376796
PNG
(CHEMBL260824)
Show SMILES CCN(Cc1ccccc1)C1CCCc2nc(cc(CC)c12)-c1c(CC)cccc1CC |w:10.10|
Show InChI InChI=1S/C30H38N2/c1-5-23-16-12-17-24(6-2)29(23)27-20-25(7-3)30-26(31-27)18-13-19-28(30)32(8-4)21-22-14-10-9-11-15-22/h9-12,14-17,20,28H,5-8,13,18-19,21H2,1-4H3
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson& Johnson PRD

Curated by ChEMBL


Assay Description
Antagonist activity at human C5a receptor in U937 cells assessed as inhibition of anaphylatoxin-induced intracellular calcium mobilization

Bioorg Med Chem Lett 18: 2544-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.049
BindingDB Entry DOI: 10.7270/Q2JM2BHD
More data for this
Ligand-Target Pair