BDBM50377279 CHEMBL257816
SMILES: CO\N=C\c1c(N)ncnc1Nc1ccc2n(Cc3cccc(F)c3)ccc2c1
InChI Key: InChIKey=DGVCIMUJVPVQEX-KBKYJPHKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50377279 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human)) | BDBM50377279
(CHEMBL257816)Show SMILES CO\N=C\c1c(N)ncnc1Nc1ccc2n(Cc3cccc(F)c3)ccc2c1 Show InChI InChI=1S/C21H19FN6O/c1-29-26-11-18-20(23)24-13-25-21(18)27-17-5-6-19-15(10-17)7-8-28(19)12-14-3-2-4-16(22)9-14/h2-11,13H,12H2,1H3,(H3,23,24,25,27)/b26-11+ | PDB
MMDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development
Curated by ChEMBL
| Assay Description
Inhibition of ErbB2 |
Bioorg Med Chem Lett 18: 3495-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.024
BindingDB Entry DOI: 10.7270/Q21G0N5V |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50377279
(CHEMBL257816)Show SMILES CO\N=C\c1c(N)ncnc1Nc1ccc2n(Cc3cccc(F)c3)ccc2c1 Show InChI InChI=1S/C21H19FN6O/c1-29-26-11-18-20(23)24-13-25-21(18)27-17-5-6-19-15(10-17)7-8-28(19)12-14-3-2-4-16(22)9-14/h2-11,13H,12H2,1H3,(H3,23,24,25,27)/b26-11+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson& Johnson Pharmaceutical Research& Development
Curated by ChEMBL
| Assay Description
Inhibition of EGFR |
Bioorg Med Chem Lett 18: 3495-9 (2008)
Article DOI: 10.1016/j.bmcl.2008.05.024
BindingDB Entry DOI: 10.7270/Q21G0N5V |
More data for this
Ligand-Target Pair | |
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