BDBM50379860 CHEMBL2011875
SMILES: C[C@@H]1C[C@H]1C(=O)Nc1snc(c1C)-c1ccc(F)cc1
InChI Key: InChIKey=OYDXPFDAFAUMMU-PRHODGIISA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 1 (Homo sapiens (Human)) | BDBM50379860 (CHEMBL2011875) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Allosteric antagonist activity at human recombinant mGluR1 expressed in AV12 cells assessed as intracellular calcium concentration using Fluo-3 dye b... | Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50379860 (CHEMBL2011875) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human mGluR5 | Bioorg Med Chem Lett 22: 2514-7 (2012) Article DOI: 10.1016/j.bmcl.2012.02.003 BindingDB Entry DOI: 10.7270/Q2RX9D3G | |||||||||||
More data for this Ligand-Target Pair |