BDBM50379990 CHEMBL2012233

SMILES: CC[C@H](N)c1oc(nc1C(=O)NCc1ccc(Cl)cc1)-c1ccc(OC)c2nc(ccc12)C(F)(F)F

InChI Key: InChIKey=MCCKQHWROTZNBD-KRWDZBQOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50379990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50379990 (CHEMBL2012233) Show SMILES CC[C@H](N)c1oc(nc1C(=O)NCc1ccc(Cl)cc1)-c1ccc(OC)c2nc(ccc12)C(F)(F)F |r| Show InChI InChI=1S/C25H22ClF3N4O3/c1-3-17(30)22-21(23(34)31-12-13-4-6-14(26)7-5-13)33-24(36-22)16-8-10-18(35-2)20-15(16)9-11-19(32-20)25(27,28)29/h4-11,17H,3,12,30H2,1-2H3,(H,31,34)/t17-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.810	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 22: 2594-7 (2012) Article DOI: 10.1016/j.bmcl.2012.01.115 BindingDB Entry DOI: 10.7270/Q2CN74X0
					More data for this Ligand-Target Pair