BDBM50380064 CHEMBL2012762

SMILES: CN(c1ccc(cc1)C(O)(c1cccn1Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=NSXAZYXFYXSEQK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50380064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50380064 (CHEMBL2012762) Show SMILES CN(c1ccc(cc1)C(O)(c1cccn1Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H23F3N2O3S/c1-30(35(33,34)23-11-6-3-7-12-23)22-16-14-21(15-17-22)25(32,26(27,28)29)24-13-8-18-31(24)19-20-9-4-2-5-10-20/h2-18,32H,19H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRalpa by scintillation proximity assa...				Bioorg Med Chem Lett 22: 2407-10 (2012) Article DOI: 10.1016/j.bmcl.2012.02.028 BindingDB Entry DOI: 10.7270/Q2M61M77
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50380064 (CHEMBL2012762) Show SMILES CN(c1ccc(cc1)C(O)(c1cccn1Cc1ccccc1)C(F)(F)F)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H23F3N2O3S/c1-30(35(33,34)23-11-6-3-7-12-23)22-16-14-21(15-17-22)25(32,26(27,28)29)24-13-8-18-31(24)19-20-9-4-2-5-10-20/h2-18,32H,19H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from LXRbeta by scintillation proximity assa...				Bioorg Med Chem Lett 22: 2407-10 (2012) Article DOI: 10.1016/j.bmcl.2012.02.028 BindingDB Entry DOI: 10.7270/Q2M61M77
					More data for this Ligand-Target Pair