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SMILES: CC[C@H]1C[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2nnn(C)n2)c2nc(C)ccc2N1C(=O)OC(C)C

InChI Key: InChIKey=RENCWUQAAWPFAB-PZJWPPBQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381436   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesteryl ester transfer protein


(Homo sapiens (Human))		BDBM50381436
PNG
(CHEMBL2017202)
Show SMILES CC[C@H]1C[C@@H](N(Cc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2nnn(C)n2)c2nc(C)ccc2N1C(=O)OC(C)C |r|
Show InChI InChI=1S/C26H29F6N7O2/c1-6-19-12-21(22-20(8-7-15(4)33-22)39(19)24(40)41-14(2)3)38(23-34-36-37(5)35-23)13-16-9-17(25(27,28)29)11-18(10-16)26(30,31)32/h7-11,14,19,21H,6,12-13H2,1-5H3/t19-,21+/m0/s1
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Article
PubMed
n/an/a 5.00E+4n/an/an/an/an/an/a



Centro de Investigaci�n Lilly

Curated by ChEMBL


Assay Description
Inhibition of CETP in human plasma assessed as reduction in fluorescent intensity by fluorescence analysis

Bioorg Med Chem Lett 22: 3056-62 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.075
BindingDB Entry DOI: 10.7270/Q28G8MQT
More data for this
Ligand-Target Pair