Found 4 hits for monomerid = 50381945 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50381945
(CHEMBL2023477)Show SMILES COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C25H25N3O6/c1-14-15(2)34-28-25(14)27-24(29)10-16-6-7-17(11-21(16)30-3)33-20-8-9-26-19-13-23(32-5)22(31-4)12-18(19)20/h6-9,11-13H,10H2,1-5H3,(H,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50381945
(CHEMBL2023477)Show SMILES COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C25H25N3O6/c1-14-15(2)34-28-25(14)27-24(29)10-16-6-7-17(11-21(16)30-3)33-20-8-9-26-19-13-23(32-5)22(31-4)12-18(19)20/h6-9,11-13H,10H2,1-5H3,(H,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of KDR |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3 [K633Q]
(Homo sapiens (Human)) | BDBM50381945
(CHEMBL2023477)Show SMILES COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C25H25N3O6/c1-14-15(2)34-28-25(14)27-24(29)10-16-6-7-17(11-21(16)30-3)33-20-8-9-26-19-13-23(32-5)22(31-4)12-18(19)20/h6-9,11-13H,10H2,1-5H3,(H,27,28,29) | NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of Flt3 |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human)) | BDBM50381945
(CHEMBL2023477)Show SMILES COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C Show InChI InChI=1S/C25H25N3O6/c1-14-15(2)34-28-25(14)27-24(29)10-16-6-7-17(11-21(16)30-3)33-20-8-9-26-19-13-23(32-5)22(31-4)12-18(19)20/h6-9,11-13H,10H2,1-5H3,(H,27,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of CSF-1R |
Bioorg Med Chem Lett 22: 3050-5 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.074
BindingDB Entry DOI: 10.7270/Q298881Z |
More data for this
Ligand-Target Pair | |
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