BDBM50385473 CHEMBL2036749

SMILES: Clc1ccc(NC(=O)N2CCN(CC3CCCNC3)CC2)cc1Cl

InChI Key: InChIKey=GQDSQCQJLXEXKL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50385473 (CHEMBL2036749) Show SMILES Clc1ccc(NC(=O)N2CCN(CC3CCCNC3)CC2)cc1Cl Show InChI InChI=1S/C17H24Cl2N4O/c18-15-4-3-14(10-16(15)19)21-17(24)23-8-6-22(7-9-23)12-13-2-1-5-20-11-13/h3-4,10,13,20H,1-2,5-9,11-12H2,(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 22: 3895-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.118 BindingDB Entry DOI: 10.7270/Q2PG1SRD
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50385473 (CHEMBL2036749) Show SMILES Clc1ccc(NC(=O)N2CCN(CC3CCCNC3)CC2)cc1Cl Show InChI InChI=1S/C17H24Cl2N4O/c18-15-4-3-14(10-16(15)19)21-17(24)23-8-6-22(7-9-23)12-13-2-1-5-20-11-13/h3-4,10,13,20H,1-2,5-9,11-12H2,(H,21,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assay				Bioorg Med Chem Lett 22: 3895-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.118 BindingDB Entry DOI: 10.7270/Q2PG1SRD
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50385473 (CHEMBL2036749) Show SMILES Clc1ccc(NC(=O)N2CCN(CC3CCCNC3)CC2)cc1Cl Show InChI InChI=1S/C17H24Cl2N4O/c18-15-4-3-14(10-16(15)19)21-17(24)23-8-6-22(7-9-23)12-13-2-1-5-20-11-13/h3-4,10,13,20H,1-2,5-9,11-12H2,(H,21,24)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysis				Bioorg Med Chem Lett 22: 3895-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.118 BindingDB Entry DOI: 10.7270/Q2PG1SRD
					More data for this Ligand-Target Pair