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SMILES: CCCN(CCC)c1cccc2nc(Nc3c(OC)cc(OC)cc3OC)c(C)cc12

InChI Key: InChIKey=SFYLYLYCCGETGG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387024   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50387024
PNG
(CHEMBL2049198)
Show SMILES CCCN(CCC)c1cccc2nc(Nc3c(OC)cc(OC)cc3OC)c(C)cc12
Show InChI InChI=1S/C25H33N3O3/c1-7-12-28(13-8-2)21-11-9-10-20-19(21)14-17(3)25(26-20)27-24-22(30-5)15-18(29-4)16-23(24)31-6/h9-11,14-16H,7-8,12-13H2,1-6H3,(H,26,27)
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Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Eisai Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assay

Bioorg Med Chem Lett 22: 4756-61 (2012)


Article DOI: 10.1016/j.bmcl.2012.05.066
BindingDB Entry DOI: 10.7270/Q21837JW
More data for this
Ligand-Target Pair