BDBM50387027 CHEMBL2046527

SMILES: COCc1cc(OC)c(Oc2nc3cccc(N(CC4CC4)CC4CCOCC4)c3cc2C)c(OC)c1

InChI Key: InChIKey=YPOLNQHEJVEKCJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50387027 (CHEMBL2046527) Show SMILES COCc1cc(OC)c(Oc2nc3cccc(N(CC4CC4)CC4CCOCC4)c3cc2C)c(OC)c1 Show InChI InChI=1S/C30H38N2O5/c1-20-14-24-25(31-30(20)37-29-27(34-3)15-23(19-33-2)16-28(29)35-4)6-5-7-26(24)32(17-21-8-9-21)18-22-10-12-36-13-11-22/h5-7,14-16,21-22H,8-13,17-19H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	762	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 4756-61 (2012) Article DOI: 10.1016/j.bmcl.2012.05.066 BindingDB Entry DOI: 10.7270/Q21837JW
					More data for this Ligand-Target Pair