BDBM50387031 CHEMBL2046531

SMILES: CCC(CC)Nc1cccc2nc(Oc3c(OC)cc(COC)cc3OC)c(C)cc12

InChI Key: InChIKey=SQMODRQGSOREHD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50387031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50387031 (CHEMBL2046531) Show SMILES CCC(CC)Nc1cccc2nc(Oc3c(OC)cc(COC)cc3OC)c(C)cc12 Show InChI InChI=1S/C25H32N2O4/c1-7-18(8-2)26-20-10-9-11-21-19(20)12-16(3)25(27-21)31-24-22(29-5)13-17(15-28-4)14-23(24)30-6/h9-14,18,26H,7-8,15H2,1-6H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 4756-61 (2012) Article DOI: 10.1016/j.bmcl.2012.05.066 BindingDB Entry DOI: 10.7270/Q21837JW
					More data for this Ligand-Target Pair