null

SMILES: NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1

InChI Key: InChIKey=RPNOCIVCNSJCFZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50387163   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Romanian Academy Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-1				Bioorg Med Chem 21: 1404-9 (2013) Article DOI: 10.1016/j.bmc.2012.11.004 BindingDB Entry DOI: 10.7270/Q2XW4M4Q
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Romanian Academy Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-2				Bioorg Med Chem 21: 1404-9 (2013) Article DOI: 10.1016/j.bmc.2012.11.004 BindingDB Entry DOI: 10.7270/Q2XW4M4Q
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Romanian Academy Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-12				Bioorg Med Chem 21: 1404-9 (2013) Article DOI: 10.1016/j.bmc.2012.11.004 BindingDB Entry DOI: 10.7270/Q2XW4M4Q
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Romanian Academy Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase-9				Bioorg Med Chem 21: 1404-9 (2013) Article DOI: 10.1016/j.bmc.2012.11.004 BindingDB Entry DOI: 10.7270/Q2XW4M4Q
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Nationale Sup£rieure de Chimie de Montpellier Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 9 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay				Bioorg Med Chem Lett 22: 4681-5 (2012) Article DOI: 10.1016/j.bmcl.2012.05.083 BindingDB Entry DOI: 10.7270/Q20866C2
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology									J Enzyme Inhib Med Chem 29: 571-81 (2014) Article DOI: 10.3109/14756366.2013.827677 BindingDB Entry DOI: 10.7270/Q2NC5ZCQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Nationale Sup£rieure de Chimie de Montpellier Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 12 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay				Bioorg Med Chem Lett 22: 4681-5 (2012) Article DOI: 10.1016/j.bmcl.2012.05.083 BindingDB Entry DOI: 10.7270/Q20866C2
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	443	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Nationale Sup£rieure de Chimie de Montpellier Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay				Bioorg Med Chem Lett 22: 4681-5 (2012) Article DOI: 10.1016/j.bmcl.2012.05.083 BindingDB Entry DOI: 10.7270/Q20866C2
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50387163 (4-ureidophenyl sulfamate ring derivative 3bb | CHE...) Show SMILES NS(=O)(=O)Oc1ccc(NC(=O)NCCc2ccccn2)cc1 Show InChI InChI=1S/C14H16N4O4S/c15-23(20,21)22-13-6-4-12(5-7-13)18-14(19)17-10-8-11-3-1-2-9-16-11/h1-7,9H,8,10H2,(H2,15,20,21)(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ecole Nationale Sup£rieure de Chimie de Montpellier Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assay				Bioorg Med Chem Lett 22: 4681-5 (2012) Article DOI: 10.1016/j.bmcl.2012.05.083 BindingDB Entry DOI: 10.7270/Q20866C2
					More data for this Ligand-Target Pair