BDBM50388277 CHEMBL2058231

SMILES: COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccncn2)c2cccc(OCC(O)=O)c2)cc1OC

InChI Key: InChIKey=PFMLCVXNUAYRKJ-BJKOFHAPSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388277   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptidyl-prolyl cis-trans isomerase FKBP5 (Homo sapiens (Human))	BDBM50388277 (CHEMBL2058231) Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccncn2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C29H33N3O9S/c1-38-25-12-10-20(16-26(25)39-2)9-11-24(21-6-5-7-22(17-21)40-18-28(33)34)41-29(35)23-8-3-4-15-32(23)42(36,37)27-13-14-30-19-31-27/h5-7,10,12-14,16-17,19,23-24H,3-4,8-9,11,15,18H2,1-2H3,(H,33,34)/t23-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Psychiatry Curated by ChEMBL					Assay Description Binding affinity to FKBP51 FK1 domain by competitive fluorescence polarization assay				J Med Chem 55: 4123-31 (2012) Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV
					More data for this Ligand-Target Pair
Peptidyl-prolyl cis-trans isomerase FKBP1A (Homo sapiens (Human))	BDBM50388277 (CHEMBL2058231) Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccncn2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C29H33N3O9S/c1-38-25-12-10-20(16-26(25)39-2)9-11-24(21-6-5-7-22(17-21)40-18-28(33)34)41-29(35)23-8-3-4-15-32(23)42(36,37)27-13-14-30-19-31-27/h5-7,10,12-14,16-17,19,23-24H,3-4,8-9,11,15,18H2,1-2H3,(H,33,34)/t23-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Psychiatry Curated by ChEMBL					Assay Description Binding affinity to FKBP12 by competitive fluorescence polarization assay				J Med Chem 55: 4123-31 (2012) Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV
					More data for this Ligand-Target Pair
FK506 binding protein 4 (Homo sapiens (Human))	BDBM50388277 (CHEMBL2058231) Show SMILES COc1ccc(CC[C@@H](OC(=O)[C@@H]2CCCCN2S(=O)(=O)c2ccncn2)c2cccc(OCC(O)=O)c2)cc1OC |r| Show InChI InChI=1S/C29H33N3O9S/c1-38-25-12-10-20(16-26(25)39-2)9-11-24(21-6-5-7-22(17-21)40-18-28(33)34)41-29(35)23-8-3-4-15-32(23)42(36,37)27-13-14-30-19-31-27/h5-7,10,12-14,16-17,19,23-24H,3-4,8-9,11,15,18H2,1-2H3,(H,33,34)/t23-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Psychiatry Curated by ChEMBL					Assay Description Binding affinity to FKBP52 FK1 domain by competitive fluorescence polarization assay				J Med Chem 55: 4123-31 (2012) Article DOI: 10.1021/jm201747c BindingDB Entry DOI: 10.7270/Q2QJ7JCV
					More data for this Ligand-Target Pair