BDBM50390114 CHEMBL2069672

SMILES: COC(C(=O)N\N=C\c1cc(OC)c(C)c(OC)c1)c1ccc2OCCOc2c1

InChI Key: InChIKey=QLWSJPVTXMDHNT-WSDLNYQXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390114 (CHEMBL2069672) Show SMILES COC(C(=O)N\N=C\c1cc(OC)c(C)c(OC)c1)c1ccc2OCCOc2c1 Show InChI InChI=1S/C21H24N2O6/c1-13-17(25-2)9-14(10-18(13)26-3)12-22-23-21(24)20(27-4)15-5-6-16-19(11-15)29-8-7-28-16/h5-6,9-12,20H,7-8H2,1-4H3,(H,23,24)/b22-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair